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When a client is receiving total parenteral nutrition (TP) therapy, how frequently should the IV tubing be changed?

  1. Every 12 hours.

  2. Every 6 hours.

  3. Every 24 hours.

  4. Every 48 hours.

The correct answer is: Every 24 hours.

When a client is receiving total parenteral nutrition (TPN), it is crucial to maintain strict standards of safety and infection control. The IV tubing used for TPN must be changed every 24 hours to minimize the risk of infections, particularly due to the high glucose content in TPN solutions which can encourage bacterial growth. This routine change helps ensure that any potential contaminants are removed and that the system remains sterile, thereby promoting the overall health and safety of the patient receiving this essential nutritional support. The choice to change IV tubing every 24 hours aligns with established guidelines for TPN administration in order to maintain quality care. The other intervals do not reflect the recommended frequency for changing TPN IV tubing. Shorter intervals, such as 6 or 12 hours, are unnecessary and may not provide added benefits, while extending the interval to 48 hours raises a significant risk for infection, making it unsuitable for clinical practice.